Description

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🧬 Hepatitis B somehow smuggles one of the smallest viral payloads into liver cells. How has it ended up being one of the deadliest diseases of all time?



💻 Rendered using @BradyJohnston ‘s open-source Molecular Nodes Add-on for Blender: https://extensions.blender.org/add-ons/molecularnodes/



📖 Primary works cited:



hristoph Seeger, William S. Mason,
Molecular biology of hepatitis B virus infection,
Virology,
2015,



https://doi.org/10.1016/j.virol.2015.02.031.
https://www.sciencedirect.com/science/article/pii/S004268221500077X



Prescott N, Biaco T, Mansisidor A …
A nucleosome switch primes hepatitis B virus infection
Cell, 2025; 188, 2111-2126.e21



Liu S, Peng N, Xie J, Hao Q, Zhang M, Zhang Y, Xia Z, Xu G, Zhao F, Wang Q, Han T, Zhu Y. Human hepatitis B virus surface and e antigens inhibit major vault protein signaling in interferon induction pathways. J Hepatol. 2015 May;62(5):1015-23. doi: 10.1016/j.jhep.2014.11.035. Epub 2014 Dec 3. PMID: 25481566.